one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the procedure of various myeloma. Its synthesis or research is critical for ensuring the purity and safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug Employed in the procedure of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets precise forms of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their examine is significant for optimizing the manufacturing process and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen 3-dihydroisoindol-2-yl)piperidine-2 receptor antagonist Utilized in the treatment of breast cancer. Several intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have different applications, which includes antiviral Attributes.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for kind two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar amounts.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in hydrochloride the synthesis of assorted gluconic acid derivatives, which are Utilized in food stuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to manage form 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).